Details for: BRIMONIDINE P
Company: AA PHARMA INC
| DIN | DIN name | Active Ingredient(s) | Strength | Dosage Form | Route of Administration |
|---|---|---|---|---|---|
| 02301334 | BRIMONIDINE P | BRIMONIDINE TARTRATE | 0.15 % / W/V | SOLUTION | OPHTHALMIC |
Consumer Information
This information was provided by the drug’s manufacturer when this drug product was approved for sale in Canada. It is designed for consumers and care givers. It is a summary of information about the drug and will not tell you everything about the drug. Contact your doctor or pharmacist if you have any questions about the drug.
What the medication is used for
BRIMONIDINE P eye drops are used to control intraocular pressure in patients with chronic open-angle glaucoma or ocular hypertension.
What it does
BRIMONIDINE P is a preserved eye drop solution that reduces the amount of fluid flowing into the eye and increases the amount of fluid flowing out of the eye. This reduces the pressure inside the eye
When it should not be used
Do not use BRIMONIDINE P:
- If you are allergic to brimonidine tartrate or any of the other ingredients (See what the nonmedicinal ingredients are)
- If you are receiving monoamine oxidase (MAO) inhibitor therapy
- In neonates and infants below the age of 2 years
What the medicinal ingredient is
Brimonidine Tartrate
What the non-medicinal ingredients are
Sodium Chlorite 25% w/v Solution Stabilized (as preservative), boric acid, calcium chloride dihydrate, carboxymethylcellulose sodium, magnesium chloride, potassium chloride, sodium borate, sodium chloride, water for injection and hydrochloric acid or sodium hydroxide to adjust the pH.
What dosage form it comes in
Ophthalmic solution, brimonidine tartrate 0.15%, w/v
Warnings and precautions
BRIMONIDINE P may cause drowsiness and fatigue or blurred
vision. Do not drive, use heavy machinery or engage in
hazardous activities or activities requiring mental alertness, until
these conditions have passed.
BEFORE you use BRIMONIDINE P talk to your doctor or
pharmacist if:
- you are breastfeeding a baby, pregnant or intend to become pregnant.
- you have any allergies to this drug, or to similar drugs (ask your doctor) or to BRIMONIDINE P’s ingredients or components of its container.
- you are taking or intend to take other prescription or nonprescription drugs. This is particularly important if you are taking medicine to lower blood pressure or to treat heart disease.
- you wear contact lenses. Lenses should be removed prior to application of BRIMONIDINE P and kept out for 15 minutes after use.
Interactions with this medication
Drugs that may interact with BRIMONIDINE P include:
Central nervous system depressants (alcohol, barbiturates,
opiates, sedatives, or anesthetics), heart and blood pressure
medications such as alpha-agonists, medication such as betablockers (ophthalmic and/or systemic), antihypertensives,
cardiac glycoside, tricyclic antidepressants and clonidine.
Drug interactions studies have not been done for
BRIMONIDINE P.
Proper use of this medication
Usual Dose
Normally, you should put one drop of BRIMONIDINE P in
each eye that needs treatment, three times daily, about 8 hours
apart, following the instructions for use below.
Do not use the bottle if the seal on the carton is broken or
missing.
Follow the following steps to help you use BRIMONIDINE P
properly:
- Wash your hands. Tilt your head back and look at the ceiling.
- Gently pull down the lower eyelid to create a small pocket.
- Turn the bottle upside down and squeeze it gently to release one drop into each eye that needs treatment.
- Let go of the lower lid, and close your eye for 30 seconds.
If a drop misses your eye, try again.
BRIMONIDINE P contains a preservative called PURITE TM. If you wear contact lenses, remove them before using BRIMONIDINE P. Wait 15 minutes after using the drops before you put your lenses back in.
Always use BRIMONIDINE P exactly as your doctor has instructed you. If you use BRIMONIDINE P with another eye drop, leave at least five minutes between putting in BRIMONIDINE P and then the other drops.
To help prevent infections, do not let the tip of the bottle touch your eye or anything else. Put the cap back on and close the bottle immediately after you have used it.
Overdose
If you accidentally use too many drops, just go back to your regular twice a day dosing the next day. If you have any concerns, talk to your doctor or pharmacist.
Missed Dose
If you forget to apply your eye drops at your normal time, simply apply them as soon as you remember. Then go back to the original schedule as directed by your doctor. Don’t try to catch up on missed drops by applying more than one dose at a time.
Side effects and what to do about them
| Very common | Occurs in more than 1 out of 10 patients |
| Common | Occurs in between 1 and 10 out of every 100 patients |
| Uncommon | Occurs in between 1 and 10 out of every 1000 patients |
The following side effects may be seen with BRIMONIDINE
P. If these persist or cause you concern, consult your doctor.
Very common:
- Red eye
- Eye allergy
- Itchy eyes
- Visual disturbance
- Small bumps on the eye surface
- Dryness of the mouth
- Burning and stinging of the eye
- Dry eyes
- A feeling that something is your eye
- Watery eyes
- Eye and eyelid swelling
- Red, itchy eyelids
- Eye pain
- Sticky eyes
- Light sensitivity
- Inflammation of the surface of the eye
- Eyesight decrease
- Headache
- Feeling weak
- Stuffy or runny nose
| Symptom / effect | Talk with your doctor, nurse, or pharmacist only if severe | Talk with your doctor, nurse, or pharmacist in all cases | Stop taking drug and talk with your doctor or pharmacist |
|---|---|---|---|
| Uncommon | |||
| Bradycardia/ heart rate decreased | ✔ | ||
| Hypotension/ blood pressure decreased | ✔ | ||
This is not a complete list of side effects. For any unexpected effects while taking BRIMONIDINE P, contact your doctor or pharmacist.
How to store
BRIMONIDINE P should be stored at 15oC to 30oC. Discard
unused solution at the end of treatment.
Keep out of the reach and sight of children.
Reporting side effects
Reporting Side Effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
- Visiting the Web page on Adverse Reaction Reporting (https://www.canada.ca/en/healthcanada/services/drugs-health-products/medeffectcanada/adverse-reaction-reporting.html) for information on how to report online, by mail or by fax; or
- Calling toll-free at 1-866-234-2345.
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.
More information
For more information, please contact your doctor, pharmacist
or other healthcare professional.
This leaflet plus the full product monograph, prepared for
health professionals, can be obtained by contacting AA
Pharma Inc. at:
1-877-998-9097
This leaflet was prepared by AA Pharma Inc.
Last revised: July 22, 2019