Details for: ARESTIN MICROSPHERES
Company: ORA PHARMA INC.
| DIN | DIN name | Active Ingredient(s) | Strength | Dosage Form | Route of Administration |
|---|---|---|---|---|---|
| 02278219 | ARESTIN MICROSPHERES | MINOCYCLINE (MINOCYCLINE HYDROCHLORIDE) | 1 MG / 4 MG | POWDER (EXTENDED RELEASE) | SUBGINGIVAL |
Consumer Information
This information was provided by the drug’s manufacturer when this drug product was approved for sale in Canada. It is designed for consumers and care givers. It is a summary of information about the drug and will not tell you everything about the drug. Contact your doctor or pharmacist if you have any questions about the drug.
What the medication is used for
ARESTIN is applied by your dental professional as part of a
deep-cleaning procedure known as scaling and root planing
(SRP). Scaling removes plaque, tartar and stains from the
surface of the teeth. Planing smoothes the rough areas on
the roots of teeth to promote healing.
Antibacterial drugs like ARESTIN treat only bacterial
infections. They do not treat viral infections. Although you
may feel better early in your treatment, ARESTIN should
be used exactly as directed. Misuse or overuse of ARESTIN
could lead to the growth of bacteria that will not be killed by
ARESTIN (resistance). This means that ARESTIN may not
work for you in the future. Do not share your medicine.
What it does
Sometimes harmful bacteria can infect the gums and form spaces or gaps around the teeth. These gaps are called pockets. While SRP has been shown to remove many of the bacteria, the instruments used during SRP sometimes can't reach stubborn bacteria that hide in the bottom of pockets. ARESTIN reduces the amount of bacteria in these pockets and helps reduce the depth of pockets around your teeth.
When it should not be used
If you are sensitive to tetracycline, doxycycline, minocycline or any other tetracycline drug.
What the medicinal ingredient is
Minocycline hydrochloride
What the non-medicinal ingredients are
Poly (glycolide-co-dl-lactide) or PGLA; this is a polymer carrier for the drug and will disappear within a month.
What dosage form it comes in
Powder (microspheres) in a cartridge
Warnings and precautions
Serious Warnings and Precautions
Teeth may become permanently discoloured if ARESTIN is used on teeth that are developing. ARESTIN should not be used in children whose teeth are developing or in pregnant or nursing women.
BEFORE you use ARESTIN talk to your dentist or periodontist if you:
- plan to be in the sun or visit a tanning salon.
- are taking oral contraceptives. Antibiotics may decrease the effectiveness of your birth control pills.
- are pregnant or nursing.
- are taking anticoagulants (blood thinners).
- are taking penicillin or other antibiotics.
- have a history of thrush (oral candidiasis).
- have diabetes, cancer, or HIV infection.
- have systemic lupus erythematosus.
Interactions with this medication
It is unlikely drugs may interact with ARESTIN since it is placed in small pockets around your teeth from which small amounts of antibiotic are released over several weeks. Speak to your dentist if you are taking anticoagulants, birth control pills or antibiotics.
Proper use of this medication
After you leave your dentist's or periodontist's office, don't
brush your teeth for 12 hours.
Don't touch the parts of your mouth where they put the
medicine for 1 week.
Don't eat hard, crunchy or sticky foods, such as apples, raw
carrots, and caramel candy for 1 week.
Don't use dental floss, dental tape or toothpicks around the
area where they put the medicine for 10 days.
It is important for you to continue with a good oral hygiene
regimen as recommended by your dentist.
Side effects and what to do about them
These are not all the possible side effects you may feel when
taking ARESTIN. If you experience any side effects not
listed here, contact your healthcare professional.
The most common side effects include:
- headache
- infection
- flu-like symptoms
- pain
| Symptom / effect | Talk with your dentist or periodontist Only if severe | Talk with your dentist or periodontist In all cases | Get immediate medical help |
|---|---|---|---|
| Very rare | |||
| Angioedema and Serious Allergic Reactions (including local allergic reactions): swelling of the face, eyes, lips, tongue or throat, trouble breathing or swallowing, itching, hives, small raised red pimples or rash (papules), redness, rash, fever, abdominal cramps | ✔ | ||
This is not a complete list of side effects. For any unexpected effects while taking ARESTIN, contact your dentist or periodontist.
How to store
Store at 25°C. Excursions permitted to 15°C to 30°C. Avoid
exposure to excessive heat.
Keep out of reach and sight of children.
Reporting side effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
- Visiting the Web page on Adverse Reaction Reporting (www.canada.ca/en/health-canada/services/drugs-health-products/medeffect-canada/adverse-reaction-reporting.html) for information on how to report online, by mail or by fax; or
- Calling toll-free at 1-866-234-2345.
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.
More information
This document plus the full product monograph, prepared for
health professionals can be found by contacting the sponsor,
OraPharma, Inc. at: 1-866-ARESTIN (273-7846).
This leaflet was prepared by OraPharma, Inc.
Last revised: November 20, 2017.