Details for: LASIX ORAL SOLUTION 10MG/ML
Company: SANOFI-AVENTIS CANADA INC
| DIN | DIN name | Active Ingredient(s) | Strength | Dosage Form | Route of Administration |
|---|---|---|---|---|---|
| 02224720 | LASIX ORAL SOLUTION 10MG/ML | FUROSEMIDE | 10 MG / ML | SOLUTION | ORAL |
Consumer Information
This information was provided by the drug’s manufacturer when this drug product was approved for sale in Canada. It is designed for consumers and care givers. It is a summary of information about the drug and will not tell you everything about the drug. Contact your doctor or pharmacist if you have any questions about the drug.
What the medication is used for
LASIX has been prescribed to you by your health provider to treat your edema (water retention) or hypertension (high blood pressure).
What it does
LASIX belongs to a group of medicines known as diuretic drugs which improve the elimination of water and salts (electrolytes) in the urine.
When it should not be used
Do not use LASIX if you are allergic to it or to any of
the components of its formulation (for list of
components see the section on “What the
nonmedicinal ingredients are”), or to any
sulfonamide-derived drugs. Ask your physician or
pharmacist if you are not sure what sulfonamidederived drugs are.
Do not use LASIX if:
What the medicinal ingredient is
Furosemide
What the non-medicinal ingredients are
10 mg/mL, oral solution: alcohol, butylated hydroxyanisol, butylated hydroxytoluene, glycerine, methylparaben, natural orange flavour, polysorbate 80, potassium sorbate, purified water, sodium hydroxide and sorbitol
What dosage form it comes in
Oral solution of 10 mg/mL
Warnings and precautions
LASIX IS A VERY STRONG WATER PILL WHICH IF GIVEN IN EXCESSIVE AMOUNTS CAN LEAD TO A PROFOUND WATER AND ELECTROLYTE LOSS FROM THE BODY. THEREFORE, CAREFUL MEDICAL SUPERVISION IS REQUIRED. THE DOSE AND DOSE SCHEDULE HAVE TO BE ADJUSTED TO THE INDIVIDUAL PATIENT’S NEEDS.
BEFORE you use LASIX talk to your health provider if:
When administered to children, LASIX therapy should be started in the hospital, in carefully selected patients, under close observation with frequent blood tests to measure electrolytes such as sodium, potassium, chloride, magnesium and calcium.
For elderly patients, (over 61 years old), the dose selection should be cautious, usually starting at the low end of dosage range, reflecting the greater frequency of decreased liver, kidney or heart function.
Studies in elderly patients with dementia have shown that taking LASIX with risperidone is associated with a higher rate of death.
The administration of LASIX to diabetic patients may result in possible decrease of diabetic control.
Dosage adjustments of the antidiabetic agent may be needed.
There have been cases of ringing in the ears, reversible and non-reversible deafness especially in children. This is most true when the patient has severe kidney disease or is taking drugs that are known to sometimes damage the ears while they are taking LASIX. Your doctor will decide if LASIX is the right medication for you/your child based on your particular condition.
LASIX should not be used in pregnant women or in women of childbearing potential unless in the opinion of the attending physician the benefits to the patient outweigh the possible risk to the foetus. Treatment during pregnancy requires monitoring of fetal growth by your doctor.
If you are suffering from hyperuricemia (high uric acid levels in your blood), taking LASIX can sometimes make a gout attack more likely.
Almost all patients can drive or operate machinery while taking LASIX, but you should not perform these tasks, which may require attention, until you know how you tolerate your medicine.
Interactions with this medication
Before using LASIX, tell your health provider about
medication you are currently taking. This way
appropriate adjustment and decision can be taken for
your treatment with LASIX.
Below are drugs or drug classes that may interact
with LASIX. These include:
Proper use of this medication
During long-term therapy a high-potassium diet may
be recommended. You should not be on a strict salt
restricted diet. Potassium supplements may be required. Your doctor will monitor your blood tests
for blood sugar, potassium and other electrolytes and
to monitor liver and kidney function. This is
especially important if you have other medical
conditions such as diabetes, take other medications or
the patient is an infant or child.
Usual dose:
Adults (oral) for edema and high blood pressure:
It is important that you take LASIX as prescribed by
your doctor.
Usually your doctor will prescribe LASIX at a dose
of 20 to 80 mg per day, which you could take as
single or 2-3 divided doses, based on the type of
administration your physician considers to be the
most appropriate for your condition.
Maximum daily dose: 200 mg.
When prescribed to children, LASIX is usually
administered in the form of a solution and at a dose
that will be determined by the health care provider.
The oral solution should be taken on an empty
stomach.
You should always respect the prescribed interval
between the doses. Never change the dose of LASIX
you are taking unless your doctor tells you to.
This drug is specifically prescribed for you or a child
in your care. Do not give it to others, even if they
have the same symptoms, and you yourself must not
use it for any condition than the one for which it was
prescribed.
Pediatrics (oral):
LASIX therapy should be instituted in the hospital, in
carefully selected patients, under close observation
with frequent monitoring of blood tests including
electrolytes. The doctor will decide what the best
dose for each child.
Orally, the initial dose should be in the range of
0.5 to 1.0 mg/kg body weight.
The total daily dose (given in divided doses of 6 to
12 hours apart) should not exceed 2 mg/kg orally. In
the newborn and in premature babies, the daily dose
should not exceed 1 mg/kg.
Overdose:
In case of drug overdose, contact a heath care
practitioner, hospital emergency department or
regional Poison Control Centre immediately, even if
there are no symptoms.
Side effects and what to do about them
Along with its beneficial effects, LASIX like all other
drugs may sometimes cause undesirable effects.
These may include: blurring of vision, constipation,
diarrhea, dizziness, dry mouth, fatigue, tachycardia,
arrhythmia (heart rhythm disturbance), feeling of
pressure in the head, increase in the amount and
frequency of your urine, leg cramps, mental
confusion, nausea, sweating, thirst, vomiting, hepatic
encephalopathy (altered mental state due to liver
disease). Talk to your doctor or pharmacist if you
experience any of the above.
Stop taking LASIX and contact your doctor
immediately if you experience an allergic reaction or
any severe side effect.
| Symptom / effect | Talk with your doctor or pharmacist immediatelyOnly if severe | Talk with your doctor or pharmacist In all cases | Stop taking drug and seek immediate emergency medical attention |
|---|---|---|---|
| Hearing problems; deafness, sometimes non-reversible | ✔ | ||
| Fever, sore throat, fatigue, lesions in the mouth or on the lips | ✔ | ||
| Skin rash and/or blistering | ✔ | ||
| Hives and/or itching | ✔ | ||
| Abdominal pain | ✔ | ||
| Difficulty to urinate | ✔ | ||
| Low blood pressure (hypotension): dizziness when rising to a standing position, impaired concentration and lightheadedness | ✔ | ||
| Yellow coloration of the skin (jaundice) | ✔ | ||
| Dehydration and/or abnormal blood tests: dryness of the mouth, thirst, weakness, dizziness, fainting or loss of consciousness, lethargy, drowsiness, restlessness, muscle pain or cramps, muscular fatigue, hypotension, racing or irregular heartbeats, nausea and vomiting, sweating, increases in blood sugar levels, increased urination, mental confusion, headache | ✔ | ||
| Muscle problems: unexplained muscle pain, tenderness, weakness, cramps | ✔ | ||
| Pseudo- Bartter syndrome: abnormal blood tests, fatigue, muscle weakness, diarrhea, dehydration, increased thirst, increased urination, low blood pressure, irregular heartbeats | ✔ | ||
| Blurred vision | ✔ | ||
| Allergic reactions: eyes sensitive to light, tingling of fingers or toes, fever | ✔ | ||
| Blood clots: pain, swelling tenderness in your leg or arm, warm, red skin and a heavy feeling in the affected area | ✔ | ||
| Failure of the kidneys: weakness, trouble breathing, swelling, fast or irregular heartbeat, confusion, decrease or inability to urinate, loss of appetite, coma and death | ✔ | ||
| In premature babies: discoloured urine and/or blood in the urine/diaper, fever and chills, vomiting, excessive crying or other signs the baby is in pain | ✔ | ||
| In premature babies: poor weight gain | ✔ |
Although not all of the above side effects are
common, if you experience one of these while you
are in the hospital or at home, talk to your doctor or
pharmacist immediately.
This is not a complete list of side effects. For any
unexpected effects while taking LASIX, contact your
doctor or pharmacist.
How to store
Store your solution at room temperature (15° –
30°C). Protect from light.
There is an expiration date on the label. Do not use
the medicine after this date.
Return any leftover solution to the pharmacist, unless
the doctor tells you to keep them at home.
Reporting side effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
- Visiting the Web page on Adverse Reaction Reporting (https://www.canada.ca/en/healthcanada/services/drugs-health-products/medeffectcanada/adverse-reaction-reporting.html) for information on how to report online, by mail or by fax; or
- Calling toll-free at 1-866-234-2345.
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.
More information
This document plus the full product monograph,
prepared for health professionals can be found at
www.sanofi.ca or by contacting the sponsor, sanofiaventis Canada Inc. at: 1-800-265-7927.
This leaflet was prepared by sanofi-aventis Canada
Inc.
Last revised: February 21, 2018