Details for: MOVAPO

MOVAPO - Supplied as ampoules
MOVAPO - Supplied as pre-filled pen

MOVAPO - Supplied as ampoules

MOVAPO may affect your ability to remain alert while doing normal everyday activities. You should avoid doing activities such as driving a car, doing physical tasks or using hazardous machinery until you know how it affects you.

Before you use MOVAPO, make sure your healthcare professional goes through the important information with you and your caregiver and shows you how to use it properly.

You or your caregiver should keep a record after each injection of how much MOVAPO you have taken or been given.

Your doctor will usually prescribe another medicine called an “antiemetic”, to take at least 2 days before you start taking MOVAPO and while you are taking MOVAPO. This will help lessen the symptoms of nausea and vomiting which can happen with MOVAPO.

MOVAPO is to be injected under the skin (subcutaneous) only. Do not inject MOVAPO into a vein.

Usual Adult Dose

Your doctor will determine the right dose for you and how often you need to take it. Take it exactly as your doctor has told you to.

Your doctor or another healthcare professional will give you the first dose.

Do not change your dose of MOVAPO or stop taking it unless your doctor has told you to.

Instruction for Use

Read these instructions carefully

What you need:

• 1 mL syringe with a ½ inch needle
• Alcohol swabs
• 1 hard-walled plastic container such as a “Sharps” bin to throw away used needles, syringes and glass ampoules. This is available from your pharmacy. Alternatively, you can use any other suitable container.

Disposable syringes and needles should be used only once and then properly thrown away. DO NOT SHARE YOUR NEEDLES.

Step 1: Opening the ampoule
Do not use the contents of the ampoule if the solution is cloudy, green, or contains particles.
Do not use it after the expiry date on the label.

Figure 1:

• Find the dot located directly above the short score mark on the thin part of the neck. This score mark is where the ampoule will break.
• Hold the bottom of the ampoule in one hand.
• Cover the dot with your thumb and use your forefinger to hold the neck of the ampoule as shown in the picture above.
• Apply pressure with your thumb and push backwards. This will snap off the top of the ampoule.
• Carefully dispose of the top of the ampoule in a “Sharps” bin.

Step 2: Preparing the Dose

• Remove the protective cap from the syringe.
• Using the opened ampoule, insert the needle into the solution. Pull back the syringe plunger to fill the syringe 0.2 to 0.3 mL past your dose.
• Check for air bubbles.
  • If bubbles are in the syringe, hold the syringe with the needle pointing up and tap the syringe with your finger to make bubbles rise to the top. Then slowly pull the syringe plunger 0.2 to 0.3 mL past your dose again and slowly push the syringe plunger until the air bubbles are gone. Repeat this step, if needed, to get rid of air bubbles.
• Slowly push the syringe plunger to the line that matches your dose of MOVAPO.

Step 3: Injecting your dose:

Remember:

• Your doctor will show you or your caregiver how to inject your dose properly
• You will have to change the place where you inject MOVAPO every time you take a dose to help avoid injection site reactions
• Choose a place on your (see Figure 2):
  • stomach
  • upper arm (right or left side)
  • upper thigh (right or left side)

Figure 2:

Hard to inject areas: There may be some areas on your body that may be hard for you to inject the drug yourself. You should ask your doctor for instructions on how to inject MOVAPO into these areas.

• Clean the site with an alcohol swab. Let it air dry.
• Hold the syringe between your thumb and fingers with one hand.
• Pinch and hold the skin and insert the needle into the skin as instructed by your doctor or nurse.
• Inject MOVAPO by holding and slowly pushing the plunger until all of the medicine has been injected.
• Remove the needle from your skin and gently rub the site. Cover the site with a bandage if it keeps bleeding.

Important: Use the contents of the ampoule on the day you have opened it. Throw away the rest. Do not reuse the contents of the opened ampoule the next day.

Proper disposal of needles, syringes and ampoules:

• Throw out all used needles, syringes and glass ampoules in a hard-walled plastic container such as a “Sharps” bin.
• Keep the cover of this container/bin closed tight and out of the reach and sight of children.
• When the container/bin is full, check with your doctor, pharmacist or nurse about proper disposal.

Overdose

If you take too much MOVAPO, you may experience more side effects than usual and they may be stronger than usual. You may experience:

• a low heart rate
• excessive sickness
• excessive sleepiness
• difficulty breathing
• You may also feel faint or dizzy particularly when you stand up, due to low blood pressure.

Missed Dose

If you miss your dose, take the next one when you next require it. Do not take another dose of MOVAPO sooner than 2 hours after the last dose. Do not take a double dose to make up for the one you missed.

MOVAPO - Supplied as pre-filled pen

MOVAPO may affect your ability to remain alert while doing normal everyday activities. You should avoid doing activities such as driving a car, doing physical tasks or using hazardous machinery until you know how it affects you.

Before you use MOVAPO, make sure your healthcare professional goes through the important information with you and your caregiver and shows you how to use it properly.

You or your caregiver should keep a record after each injection of how much MOVAPO you have taken or been given.

Your doctor will usually prescribe another medicine called an “antiemetic”, to take at least 2 days before you start taking MOVAPO and while you are taking MOVAPO. This will help lessen the symptoms of nausea and vomiting which can happen with MOVAPO.

MOVAPO is to be injected under the skin (subcutaneous) only. Do not inject MOVAPO into a vein.

Usual Adult Dose

Your doctor will determine the right dose for you and how often you need to take it. Take it exactly as your doctor has told you to.

Your doctor or another healthcare professional will give you the first dose.

Do not change your dose of MOVAPO or stop taking it unless your doctor has told you to.

Instruction for Use

Figure 1 shows the different parts of the pen. You should familiarise yourself with its parts.

Figure 1:

What you need:

• 1 pre-filled pen
• 1 Pen needle. [Note: the pack does not contain needles. You can use the same needles that are used for insulin pens to use with your MOVAPO Pen].
• 2 alcohol swabs
• 1 hard-walled plastic container such as a “Sharps” bin to throw away used needles. This is available from your pharmacy. Alternatively, you can use any other suitable container.

The disposable pen needles should be used only once and then properly thrown away. DO NOT SHARE YOUR NEEDLES.

Read these instructions carefully.

Important: Do not pull the dosage dial/plunger (see 1 in Figure 1) before you have set the dose you need.

Step 1: Attach the pen needle

Do not use the pen if the solution in the cartridge is cloudy, green or contains particles.

Do not use after the expiry date on the label.

• Before you attach the pen needle to the Pen you will need an alcohol swab and one pen needle. Do not remove the needle from its protective cone (see Figure 1). Take the Pen out of its box and remove the outer sleeve (see Figure 2).

Figure 2:

• Wipe the membrane (see Figure 3) with an alcohol swab.

Figure 3:

• Peel off the paper from the protective cone (see Figure 4). Screw the cone onto the membrane by turning it to the right (clockwise). This will attach the needle securely to the Pen (see Figure 5).

PLEASE NOTE

It is important to bring the needle protective cone to the Pen in a straight line, as shown in Figure 5. This will attach the needle securely. If the protective cone is brought in and attached at an angle it may cause the Pen to leak.

• Remove the protective cone (see Figure 6). Do not throw it away. Do not remove the needle protector at this stage (see 7 in Figure 1).

Figure 6:

• Put back the Pen’s outer sleeve.

Step 2: Select your dose

• Press the dosage dial and turn it to the right (clockwise) until the arrow points to the dose your doctor told you to take (see Figure 7).
• Let go of the dial. The dose is now set. You do not have to set the dial again for subsequent doses.
• Never pull and turn the dial at the same time.

Important: If you pass the dose you need while turning the dial, just continue pressing and turning the dial to the right until you arrive at it again.

Figure 7:

If your dose is 1 mg: it is necessary to “prime” the Pen before injecting the first dose. First load the dose (see Step 3). Then remove the needle protector from the needle (see Figure 10).
Finally, press the dosage dial down as far as it will go and empty the first 1 mg dose onto a paper tissue.

If your first dose is more than 1 mg: you do not need to “prime” the pen.

Step 3: Load your dose

• Load your dose by pulling the dosage dial out (see Figure 8) as far as it will go.
• When the dosage dial is pulled as far as it will go, you should see a number scale on the plunger. The highest number that you see on the plunger must match the dose you have set on the dosage dial. This ensures that the correct dose has been loaded. Only inject your dose if the number on the plunger scale is the same as the number on the dosage dial.
• Never try to change the dose when the Pen is in the “loaded” position. If the wrong dose has been selected, you will have to discard the incorrect dose into a paper towel and reset the dosage dial to the correct dose. Follow the instructions under “Step 2: How to select your dose” again.

Figure 8:

Step 4: Inject your dose
Remember:

• Your doctor will show you or your caregiver how to inject your dose properly
• You will have to change the place where you inject MOVAPO every time you take a dose to help avoid injection site reactions
• Choose a place on your: (see Figure 9)
  • stomach
  • upper arm (right or left side)
  • upper thigh (right or left side)

Figure 9:

Hard to inject areas: There may be some areas on your body that may be hard for you to inject the drug yourself. You should ask your doctor for instructions on how to inject MOVAPO into these areas.

• Using an alcohol swab, clean the area of skin where you will be injecting the dose.
• Remove the Pen’s outer sleeve.
• Remove the needle protector (see Figure 10).

Figure 10:

• Insert the needle into the skin as your doctor has shown you or your caregiver to do. (see Figure 11).

Figure 11:

• Press the dosage dial down as far as it will go, using your thumb. Once the dosage dial is fully pressed, count to 3 before taking the needle out.
• Remove and throw away the needle:
  • attach the protective cone back onto the used needle, and push it gently into place
  • once it is secure, you can unscrew the needle by turning it to the left (counter clockwise) (see Figure 12 and 13)
  • throw away the needle in the hard walled plastic container.

Step 5: Preparing the Pen for the next injection
Check that there is enough apomorphine left in the cartridge for the next injection (see 4 in Figure 1).

• If there is, follow Step 1: and attach a new needle. Put back the outer sleeve of the Pen (see Figure 14). Remember do not throw away the protective cone.
• If there is not enough apomorphine left for another injection, prepare another Pen (follow Step 1: and Step 2:).

Figure 14:

Overdose

If you take too much MOVAPO, you may experience more side effects than usual and they may be stronger than usual. You may experience:

• a low heart rate
• excessive sickness
• excessive sleepiness
• difficulty breathing
• You may also feel faint or dizzy particularly when you stand up, due to low blood pressure.

Missed Dose

If you miss your dose, take the next one when you next require it. Do not take another dose of MOVAPO sooner than 2 hours after the last dose. Do not take a double dose to make up for the one you missed.