Details for: AA-DILTIAZ
Company: AA PHARMA INC
| DIN | DIN name | Active Ingredient(s) | Strength | Dosage Form | Route of Administration |
|---|---|---|---|---|---|
| 00771376 | AA-DILTIAZ | DILTIAZEM HYDROCHLORIDE | 30 MG | TABLET | ORAL |
| 00771384 | AA-DILTIAZ | DILTIAZEM HYDROCHLORIDE | 60 MG | TABLET | ORAL |
Consumer Information
This information was provided by the drug’s manufacturer when this drug product was approved for sale in Canada. It is designed for consumers and care givers. It is a summary of information about the drug and will not tell you everything about the drug. Contact your doctor or pharmacist if you have any questions about the drug.
What the medication is used for
AA-DILTIAZ is used for:
- the management of angina resulting from coronary artery spasm
- the management of effort-associated angina (chest pain)
What it does
AA-DILTIAZ belongs to the group of drugs called “calcium channel blockers” or “calcium antagonists”.
AA-DILTIAZ relaxes the arteries, thereby lowering blood pressure.
AA-DILTIAZ reduces the amount of oxygen that your heart muscle needs. This helps control chest pain.
When it should not be used
Do not use AA-DILTIAZ if:
- You are pregnant or plan to become pregnant.
- You are breastfeeding.
- You have a known allergy to diltiazem or to any of the non-medicinal ingredients.
- You have very low blood pressure (< 90 mmHg systolic).
- You have very slow heartbeat (40 beats/minute or less)
- You have heart rhythm disorders in the absence of a pacemaker.
- You have severe heart failure with fluid in the lungs.
- You are taking a medicine called dantrolene used for severe muscle spasms or severe fever.
- You are using ivabradine
What the medicinal ingredient is
Diltiazem Hydrochloride
What the non-medicinal ingredients are
colloidal silicon dioxide, FD&C blue #1 (30 mg tablet only), FD&C yellow #6 (60 mg tablet only), D&C yellow #10, hydroxypropyl methylcellulose, lactose, magnesium stearate, polyethylene glycol and titanium dioxide
What dosage form it comes in
Tablets: 30 mg and 60 mg.
Warnings and precautions
Serious Warnings and Precautions
BEFORE you use AA-DILTIAZ talk to your doctor or pharmacist if:
- You have very low blood pressure.
- You have ever had a bad or unusual reaction to any drug containing diltiazem in the past.
- You have heart, liver, or kidney disease.
- You have high blood sugar or diabetes.
- You are 65 years or older.
- You have a history of heart failure, new shortness of breath, slow heartbeat or low blood pressure. Cases of kidney injury in patients with such conditions have been reported.
Interactions with this medication
As with most medicines, interactions with other drugs are possible. Tell your doctor, nurse, or pharmacist about all the medicines you take, including drugs prescribed by other doctors, vitamins, minerals, natural supplements, or alternative medicines.
Additional monitoring of your dose or condition may be needed if you are taking other drugs.
The following may interact with AA-DILTIAZ: Antifungal medications with a name ending in azole;
- Medications used to control the immune system such as cyclosporine;
- Certain antibiotics should not be taken with AA- DILTIAZ such as erythromycin, rifampin. Check with your pharmacist if not sure;
- Sleeping pills such as benzodiazepines (midazolam, triazolam);
- Other blood pressure medications: alpha antagonists, beta-blockers;
- Heart medications: Amiodarone, digoxin, digitalis, flecainide, nifedipine, propafenone, quinidine, verapamil; ivabradine
- Anaesthetics;
- Lithium and imipramine used for some types of mental illness;
- Drugs that dilate the blood vessels: short and long acting nitrates;
- Medications used to control seizures:
- carbamazepine, phenobarbital, phenytoin;
- Warfarin used as anticoagulant;
- Cholesterol lowering medications: statins;
- Theophylline used for breathing problems;
- Terfenadine or ranitidine used for allergies;
- Medications used to control stomach ulcers such as cimetidine will increase the effects of AA-DILTIAZ
- Drugs to treat inflammation: corticosteroids, methylprednisolone;
- Dantrolene used for severe muscle spasms or severe fever.
- Acetylsalicylic acid (Aspirin) or antiplatelet drugs such as ticagrelor, cilostazol, clopidogrel, dipyridamole, ticlopidine.
- X-Ray contrast agents.
Alcohol may cause low blood pressure and dizziness when you go from lying or sitting to standing up. This can especially occur after the first dose and when the dose is increased. Tell your doctor if you experience dizziness, light- headedness, fainting, decreased blood pressure or increased heart rate.
Grapefruit juice when consumed too often while taking AA- DILTIAZ may cause headache, irregular heartbeat, edema (swelling), unexplained weight gain, and chest pain. Tell your doctor if this happens to you. Your doctor may recommend that grapefruit juice be avoided if this happens to you.
Proper use of this medication
Do not miss doses or take extra doses, unless your doctor tells you. If you are not clear about the directions, ask your doctor or pharmacist.
Take AA-DILTIAZ exactly as your doctor tells you.
If you have Chronic Stable Angina or Vasospastic Angina:
Adult Dose:
Usual starting dose
Take a 30 mg tablet 4 times a day, before your meals and at bedtime. Your doctor may increase your dose if needed. Do NOT chew or crush the tablet.
If you have Unstable Angina Pectoris and are in the Intensive Care Unit:
Adult Dose:
Your doctor will determine your dose and how often you will be given it.
Overdose
If you think you have taken too much AA-DILTIAZ, contact health care professional hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms
Missed Dose
If a dose of this medication has been missed, it should be taken as soon as possible. However, if it is almost time for the next dose, skip the missed dose and go back to the regular dosing schedule.
Side effects and what to do about them
Side effects may include:
- Headache, dizziness, malaise;
- Nausea (feeling like vomiting);
- Flushing (facial redness) or feeling unusually warm;
- Unusual tiredness and weakness;
- Upset stomach.
AA-DILTIAZ can cause abnormal blood results. Your doctor will decide when to perform blood tests and will interpret the results.
| Symptom / effect | Talk to your healthcare professional Only if severe | Talk to your healthcare professional In all cases | Stop taking drug and get immediate medical help |
|---|---|---|---|
| Common | |||
| Low Blood Pressure: dizziness, fainting, light- headedness. May occur when you go from lying or sitting to standing up. | ✔ | ||
| Fast, slow, or irregular heartbeat | ✔ | ||
| Peripheral edema: swelling of the ankles | ✔ | ||
| Respiratory tract infection: pharyngitis, rhinitis | ✔ | ||
| Allergic Reaction: rash, hives, swelling of the face, lips, tongue or throat, difficulty swallowing or breathing | ✔ | ||
| Uncommon | |||
| Depression: low mood, lack of interest in usual activities, change in sleep and appetite. | ✔ | ||
| Heart block: A disease in the electrical system of the heart causing lightheaded ness, fainting and irregular heartbeat. | ✔ | ||
| Heart Attack: shortness of breath, chest pain | ✔ | ||
| Angina: Chest pain | ✔ | ||
| Heart Failure: shortness of breath, leg swelling, and exercise intolerance. | ✔ | ||
| Eye Problems: decreased vision, irritation, sore red eyes | ✔ | ||
| Increased blood sugar: frequent urination, thirst, and hunger | ✔ | ||
| Rare | |||
| Liver Disorder: yellowing of the skin or eyes, dark urine, abdominal pain, nausea, vomiting, loss of appetite | ✔ | ||
| Unknown | |||
| Serious Skin Reactions (Stevens- Johnson Syndrome, Toxic Epidermal Necrolysis, hypersensi- tivity Syndrome): any combination of itchy skin rash, redness, blistering and peeling of the skin and /or of the lips, eyes, mouth, nasal passages or genitals, accompanied by fever, chills, headache, cough, body aches or joint pain, yellowing of the skin or eyes, dark urine. | ✔ | ||
This is not a complete list of side effects. For any unexpected effects while taking AA-DILTIAZ, contact your doctor or pharmacist.
How to store
Store at room temperature 15°C to 30°C.
Keep out of sight and reach of children.
Reporting side effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
- Visiting the Web page on Adverse Reaction Reporting for information on how to report online, by mail or by fax; or
- Call toll-free at 1-866-234-2345
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.
More information
If you want more information about AA-DILTIAZ:
- Talk to your doctor or pharmacist.
- Find the full product monograph that is prepared for healthcare professionals and includes this Consumer Information by visiting the Health Canada website. Find the Consumer Information on the manufacturer’s website, or by calling 1-877-998-9097.
This leaflet was prepared by AA Pharma Inc.
Date prepared: April 24, 2020