Details for: AVIANE
Company: TEVA CANADA LIMITED
DIN | DIN name | Active Ingredient(s) | Strength | Dosage Form | Route of Administration |
---|---|---|---|---|---|
02298538 | AVIANE 21 | LEVONORGESTREL; ETHINYL ESTRADIOL | 100 MCG; 20 MCG | TABLET | ORAL |
02298546 | AVIANE 28 | LEVONORGESTREL; ETHINYL ESTRADIOL | 100 MCG; 20 MCG | TABLET | ORAL |
Summary Reports
Summary Safety Review - Hormonal Birth Control Products (excluding Emergency Birth Control Products) - Assessing the Potential Risk of Suicidal Thoughts and Behaviours (suicidality)
Consumer Information
This information was provided by the drug’s manufacturer when this drug product was approved for sale in Canada. It is designed for consumers and care givers. It is a summary of information about the drug and will not tell you everything about the drug. Contact your doctor or pharmacist if you have any questions about the drug.
What the medication is used for
- To prevent pregnancy
- To treat moderate acne in women 14 years of age and older who are able to use birth control pills, desire birth control and have achieved menarche. Your first menstrual period is referred to as menarche.
What it does
AVIANE is a birth control pill (oral contraceptive) that contains two female sex hormones (levonorgestrel and ethinyl estradiol). It has been shown to be highly effective in preventing pregnancy when taken as prescribed by your doctor. Pregnancy is always more risky than taking birth control pills except in smokers older than age 35.
Birth control pills work by inhibiting the monthly release of an egg(s) by the ovaries. Some studies have demonstrated changes in the endometrium (lining of the womb) and mucus produced by the cervix (opening of the uterus) with the use of birth control pills.
Effectiveness of Birth Control Pills:
Combination birth control pills are more than 99 percent effective in preventing pregnancy when:
- the pill is TAKEN AS DIRECTED, and
- the amount of estrogen is 20 micrograms or more
A 99 percent effectiveness rate means that if 100 women used
birth control pills for one year, one woman in the group would
get pregnant.
The chance of becoming pregnant increases with incorrect use.
Other Ways to Prevent Pregnancy
Other methods of birth control are available to you. They are usually less effective than birth control pills. When used properly, however, other methods of birth control are effective enough for many women.
The following table gives reported pregnancy rates for various forms of birth control, including no birth control. The reported rates represent the number of women out of 100 who would become pregnant in one year.
Reported Pregnancies per 100 Women per Year:

Pregnancy rates vary widely because people differ in how
carefully and regularly they use each method. (This does not
apply to IUDs since they are implanted in the uterus). Regular
users may achieve pregnancy rates in the lower ranges. Others
may expect pregnancy rates more in the middle ranges.
The effective use of birth control methods other than birth
control pills and IUDs requires more effort than taking a
single pill every day. It is an effort that many couples
undertake successfully.
When it should not be used
The birth control pill is not suitable for every woman. In a small number of women, serious side effects may occur. Your doctor can advise you if you have any conditions that would pose a risk to you. If you see a different doctor, inform him/her that you are taking birth control pills. Tell the doctor that your birth control pills are AVIANE. The use of the birth control pill should always be supervised by your doctor.
You should not use AVIANE if you have or have had any of the following conditions:
- History of or actual heart attack, chest pain (angina pectoris) or stroke;
- Blood clots in the legs (thrombophlebitis), lungs (pulmonary embolism), eyes or elsewhere;
- Hereditary or acquired blood clotting disorders;
- Known or suspected cancer of the breast, sex organs, or certain estrogen-dependent cancers;
- Unexplained vaginal bleeding (until a diagnosis is reached by your doctor);
- Partial or complete loss of vision or other vision problems caused by vascular disease (blood vessel disease of the eye);
- History of or actual liver disease or history of or actual benign or malignant liver tumor;
- Jaundice (yellowing of the skin and eyes) or liver disease if still present;
- Heart valve or heart rhythm disorders that may be associated with formation of blood clots;
- Diabetes affecting your circulation;
- Migraines (current or history) with neurological symptoms such as aura (visual or sensory disturbance);
- Uncontrolled high blood pressure;
- Hypersensitivity(allergy) to any of the components of AVIANE (levonorgestrel and ethinyl estradiol tablets) (see What the important nonmedicinal ingredients are);
- Known or suspected pregnancy. Birth control pills should never be taken if you think you are pregnant. They will not prevent the pregnancy from continuing. There is no conclusive evidence, however, that the pill can damage a developing child when taken inadvertently during early pregnancy.
- Pancreatitis associated with severe hypertriglyceridemia (current or history). Pancreatitis is the inflammation of the pancreas, marked by abdominal pain, whereas severe hypertriglyceridemia is a very high level of triglycerides in the blood, and may show no symptoms.
- Are using anti-viral medications to treat Hepatitis C Virus (HCV) which contain combination of ombitasvir paritaprevir, ritonavir and dasabuvir with or without ribavirin
What the medicinal ingredient is
Levonorgestrel and Ethinyl Estradiol
What the non-medicinal ingredients are
Each active orange tablet contains the following non
medicinal ingredients:
FD & C yellow # 6 aluminium lake, hydroxypropyl
methylcellulose (HPMC), lactose monohydrate, magnesium
stearate, microcrystalline cellulose, polyethylene glycol,
pregelatinized starch, sodium starch glycolate and titanium
dioxide.
Each inert light-green tablet contains the following non
medicinal ingredients:
D & C Yellow # 10 aluminium lake, FD & C Yellow # 6
aluminium lake, FD & C Blue # 1 aluminium lake, lactose
monohydrate, magnesium stearate, microcrystalline cellulose
and pregelatinized starch.
What dosage form it comes in
AVIANE (levonorgestrel and ethinyl estradiol) tablets are
available in a 21-day regimen (AVIANE 21) and a 28-day
regimen (AVIANE 28)
AVIANE 21: Each package contains 21 orange tablets. Each
orange tablet contains 0.10 mg levonorgestrel and 0.02 mg
ethinyl estradiol.
AVIANE 28: Each package contains 21 orange tablets and 7
light green tablets. Each orange tablet contains 0.10 mg
levonorgestrel and 0.02 mg ethinyl estradiol. The light green
tablets are inactive.
Warnings and precautions
Serious Warnings and Precautions
Cigarette smoking increases the risk of serious adverse effects on the heart and blood vessels. This risk increases with age and becomes significant in birth control pill users over 35 years of age. Women who use birth control pills should not smoke.
Birth control pills DO NOT PROTECT against sexually transmitted infections (STIs), including HIV/AIDS.
For protection against STIs, it is advisable to use latex or polyurethane condoms IN COMBINATION WITH birth control pills.
There are also conditions that your doctor will want to watch closely or that might cause your doctor to recommend a method of contraception other than birth control pills.
BEFORE you use AVIANE talk to your doctor or pharmacist if the following apply to you:
- Breast conditions
- A strong family history of breast cancer
- Breast disorders including pain, discharge from the nipples, thickenings, or lumps. In some circumstances, benefit may be derived from taking the pill; in other cases, adverse effects may follow.
- Diabetes
- High blood pressure
- Abnormal levels of fats in the bloodstream (high cholesterol or triglycerides)
- Cigarette Smoking
- Heart or kidney disease
- Epilepsy/seizures
- History of Depression
- Fibroid tumours of the uterus
- Gallbladder or pancreatic disease
- History of liver disease or jaundice
- Family history of blood clots, heart attacks or strokes.
- May be pregnant or breast feeding
- Have systemic lupus erythmatosus
- Have inflammatory bowel disease such as Crohn’s disease or ulcerative colitis
- Have haemolytic uremic syndrome
- Have sickle cell disease
- Have problems with the valves in your heart and/or have irregular heart rhythm
- Wear contact lenses
- Have Hepatitis C
If you see a different doctor, inform him or her that you are
using AVIANE.
Tell your doctor if you are scheduled for any laboratory tests
since certain blood tests may be affected by hormonal
contraceptives.
Also tell your doctor if you are scheduled for MAJOR
surgery, recent delivery, or second-trimester abortion. You
should consult your doctor about stopping the use of AVIANE
four weeks before major surgery and not using AVIANE for a
time period after surgery or during prolonged bed rest.
AVIANE should be used only under the supervision of a
doctor, with regular follow-up to identify side effects
associated with its use. Your visits may include a blood
pressure check, a breast exam, an abdominal exam and a
pelvic exam, including a Pap smear. Visit your doctor three
months or sooner after the initial examination. Afterward, visit
your doctor at least once a year.
Use AVIANE only on the advice of your doctor and carefully
follow all directions given to you. You must use the birth
control pill exactly as prescribed. Otherwise, you may become
pregnant. If you and your doctor decide that, for you, the
benefits of AVIANE outweigh the risks, you should be aware
of the following:
THE RISKS OF USING BIRTH CONTROL PILLS
1. Circulatory disorders (including blood clot in legs, lungs, heart, eyes or brain)
Women who use hormonal contraceptives have a higher
incidence of blood clots. Blood clots are the most
common serious side effects of birth control pills. The
risk of developing clots is especially high during the first
year a woman ever uses a hormonal contraceptive. Clots
can occur in many areas of the body.
Be alert for the following symptoms and signs of serious
adverse effects. Call your doctor immediately if they
occur:
- Sharp pain in the chest, coughing blood, or sudden shortness of breath. These symptoms could indicate a possible blood clot in the lung;
- Pain and/or swelling in the calf. These symptoms could indicate a possible clot in the leg;
- Crushing chest pain or heaviness. These symptoms could indicate a possible heart attack;
- Sudden severe or worsening headache or vomiting, dizziness or fainting, disturbances of vision or speech, or weakness or numbness in an arm or leg. These symptoms could indicate a possible stroke;
- Sudden partial or complete loss of vision. This symptom could indicate a blood clot in the eye.
Any of these conditions can cause death or disability.
Clots also occur rarely in the blood vessels of the eye,
resulting in blindness or impaired vision or in a blood
vessel leading to an arm or leg, resulting in damage to or
loss of a limb.
The risk of clotting seems to increase with higher
estrogen doses. It is important, therefore, to use as low
a dosage of estrogen as possible.
2. Breast cancer
The most significant risk factors for breast cancer are
increasing age and a strong history of breast cancer in the
family (mother or sister). Other established risk factors
include obesity, never having children, and having your first
full-term pregnancy at a late age.
Some women who use birth control pills may be at increased
risk of developing breast cancer before menopause, which
occurs around age 50. These women may be long-term users
of birth control pills (more than eight years) or women who
start using Birth control pills at an early age. In a few women,
the use of Birth control pills may accelerate the growth of an
existing but undiagnosed breast cancer. Early diagnosis,
however, can reduce the effect of breast cancer on a woman’s
life expectancy. The potential risks related to birth control
pills seem to be small, however; a yearly breast examination
by a doctor is recommended for all women.
ASK YOUR DOCTOR FOR ADVICE AND INSTRUCTIONS ON REGULAR SELF-EXAMINATION OF YOUR BREASTS.
3. Cervical cancer
Some studies have found an increase of cancer of the cervix
in women who use hormonal contraceptives, although this
finding may be related to factors other than the use of oral
contraceptives. However, there is insufficient evidence to
rule out the possibility that oral contraceptives may cause
such cancers.
Chronic infection with the Human Papilloma Virus (HPV) is
believed to be the most important risk factor for cervical
cancer. In women who use COCs for a long time the chance
of getting cervical cancer may be slightly higher. This
finding may not be caused by the Pill itself but may be
related to sexual behaviour and other factors.
4. Liver tumours
The short and long-term use of birth control pills have
also been linked with the growth of liver tumours or liver injury
(e.g., hepatitis, hepatic function abnormal). Such
injury or tumours are extremely rare.
Contact your doctor immediately if you experience
nausea, vomiting, severe pain or a lump in the abdomen.
5. Gallbladder disease
Users of birth control pills have a greater risk of developing gallbladder disease requiring surgery within the first year of use. The risk may double after four or five years of use.
6. Use in pregnancy
Birth control pills should not be taken by pregnant women. They will not prevent the pregnancy from continuing. There is no evidence, however, that the birth control pill can damage a developing child. You should check with your doctor about risks to your unborn child from any medication taken during pregnancy.
7. Use after pregnancy, miscarriage or an abortion
Your doctor will advise you of the appropriate time to start the use of AVIANE after childbirth, miscarriage, or therapeutic abortion.
8. Pregnancy after stopping AVIANE
You will have a menstrual period when you stop using AVIANE. You should delay pregnancy until another menstrual period occurs within four to six weeks. In this way the pregnancy can be more accurately dated. Contact your doctor for recommendations on alternate methods of contraception during this time.
9. Use while breast-feeding
If you are breast-feeding, consult your doctor before starting the birth control pill. The hormones in birth control pills are known to appear in breast milk. Adverse effects on the child have been reported, including yellowing of the skin (jaundice) and breast enlargement. You should use another method of contraception. The use of oral contraceptives is generally not recommended until the nursing mother has completely weaned her child.
Interactions with this medication
Certain drugs may interact with birth-control pills to make them less effective in preventing pregnancy or cause an increase in breakthrough bleeding. You may also need to use a nonhormonal method of contraception during any cycle in which you take drugs that can make oral contraceptives less effective.
Drugs that may interact with AVIANE include:
- drugs used for epilepsy such as barbiturates (e.g. phenobarbital) and phenytoin, primidone, topiramate, carbamazepine
- certain drugs used in the treatment of tuberculosis (eg. rifampicin, rifabutin)
- drugs used for HIV or AIDS such as ritonavir
- herbal products containing St. John’s Wort (Hypericum perforatum)
- antibiotics (e.g. penicillins, tetracyclines) for infectious diseases
- cyclosporine
- antifungals (griseofulvin)
- cholesterol-lowering drugs (eg. clofibrate)
- antihypertensive drugs (for high blood pressure)
- antidiabetic drugs and insulin (for diabetes)
- prednisone
- sedatives and hypnotics (eg, benzodiazepines, barbiturates, chloral hydrate, glutethimide, meprobamate)
- antidepressants (e.g. clomipramine)
- other drugs such as phenylbutazone, analgesics, modafinil, troleandomycin, Vitamin E and Vitamin B12.
- anti-viral hepatitis C virus (HCV) medicinal products such as ombitasvir, paritaprevir, ritonavir and dasabuvir, with or without ribavirin.
Please inform your doctor and pharmacist if you are taking or have recently taken any other drugs or herbal products, even those without a prescription. Also, tell any other doctor or dentist who prescribes another drug (or the dispensing pharmacist) that you use AVIANE. They can tell you if you need to use an additional method of contraception and if so, for how long.
This is not a complete list of possible drug interactions with AVIANE. Talk to your doctor for more information about drug interactions.
Proper use of this medication
HOW TO TAKE AVIANE:
1. READ THESE DIRECTIONS
- Before you start taking your pills, and
- Any time you are not sure what to do.
2. LOOK AT YOUR PILL PACK to see if it has 21 or 28 pills:
- 21-Pill Pack: 21 active pills (with hormones) taken daily for three weeks, and then no pills taken for one week;

or
- 28-Pill Pack: 21 active pills (with hormones) taken daily for three weeks, and then seven “reminder” pills (no hormones) taken daily for one week.

3. You may wish to use a second method of birth control (e.g. latex condoms and spermicidal foam or gel) for the first seven days of the first cycle of pill use. This will provide a back-up in case pills are forgotten while you are getting used to taking them.
4. When receiving any medical treatment, be sure to tell your doctor that you are using birth control pills.
5. MANY WOMEN HAVE SPOTTING OR LIGHT BLEEDING, OR MAY FEEL SICK TO THEIR STOMACH DURING THE FIRST THREE MONTHS ON THE PILL. If you do feel sick, do not stop taking AVIANE. The problem will usually go away. If it does not go away, check with your doctor or clinic.
6. MISSING PILLS ALSO CAN CAUSE SOME SPOTTING OR LIGHT BLEEDING, even if you make up the missed pills. You also could feel a little sick to your stomach on the days you take two pills to make up for missed pills.
7. IF YOU MISS PILLS AT ANY TIME, YOU COULD GET PREGNANT. THE GREATEST RISKS FOR PREGNANCY ARE:
- when you start a pack late, or
- when you miss pills at the beginning or at the very end of the pack.
8. ALWAYS BE SURE YOU HAVE READY:
- ANOTHER KIND OF BIRTH CONTROL (such as latex condoms and spermicidal foam or gel) to use as a back-up in case you miss pills, and
- AN EXTRA PACK OF PILLS.
9. IF YOU EXPERIENCE VOMITING OR DIARRHEA, OR IF YOU TAKE CERTAIN MEDICINES, such as antibiotics, your pills may not work as well. Use a backup method, such as latex condoms and spermicidal foam or gel, until you can check with your doctor or clinic.
10. IF YOU FORGOT MORE THAN ONE PILL TWO MONTHS IN A ROW, talk to your doctor or clinic about how to make pill-taking easier or about using another method of birth control.
11. IF YOUR QUESTIONS ARE NOT ANSWERED HERE, CALL YOUR DOCTOR OR CLINIC.
WHEN TO START THE FIRST PACK OF PILLS BE SURE TO READ THESE INSTRUCTIONS:
- before you start taking your pills, and
- any time you are not sure what to do.
Decide with your doctor or clinic what is the best day for you to start taking your first pack of pills. Your pills may be either a 21-day or a 28-day type.
A. 21-DAY COMBINATION With this type of birth control pill, you are on pills for 21 days and off pills for seven days. You must not be off the pills for more than seven days in a row.
1. THE FIRST DAY OF YOUR MENSTRUAL PERIOD
(BLEEDING) IS DAY 1 OF YOUR CYCLE.
Your doctor may advise you to start taking the pills on Day 1, on Day 5, or
on the first Sunday after your period begins. If your period
starts on Sunday, start that same day. If AVIANE Tablets
administration is initiated after Day 1 of the first menstrual
cycle or postpartum, contraceptive reliance should not be
placed on AVIANE until after the first seven active tablets
have been taken for seven consecutive days. Nonhormonal methods of contraception (such as latex condoms and
spermicidal foam or gel) should be used for the first 7 days of
tablet taking.
2. Take one pill at approximately the same time every day for 21 days. THEN TAKE NO PILLS FOR SEVEN DAYS. Start a new pack on the eighth day. You will probably have a period during the seven days off the pill. (This bleeding may be lighter and shorter than your usual period).
TWO WAYS TO REMEMBER IN WHAT ORDER TO
TAKE THE PILLS
1. Follow the days of the week (as shown above the pills).
2. Always finish the orange tablets before going onto the
week when you are off pills.
B. 28-DAY COMBINATION
With this type of birth control pill, you take 21 pills that contain hormones and seven pills that contain no hormones.
1. THE FIRST DAY OF YOUR MENSTRUAL PERIOD (BLEEDING) IS DAY 1 OF YOUR CYCLE. Your doctor may advise you to start taking the pills on Day 1, on Day 5, or on the first Sunday after your period begins. If your period starts on Sunday, start that same day. If AVIANE Tablets administration is initiated after Day 1 of the first menstrual cycle or postpartum, contraceptive reliance should not be placed on AVIANE until after the first seven active tablets have been taken for seven consecutive days. Nonhormonal methods of contraception (such as latex condoms and spermicidal foam or gel) should be used for the first 7 days of tablet taking.
2. Take one pill at approximately the same time every day for 28 days. Begin a new pack the next day, NOT MISSING ANY DAYS. Your period should occur during the last seven days of using that pill pack.
TWO WAYS TO REMEMBER IN WHAT ORDER TO
TAKE THE PILLS
1. Follow the days of the week (as shown above the pills).
2. Always finish the orange tablets before going onto the
light-green inactive pills.
WHAT TO DO DURING THE MONTH
1. TAKE A PILL AT APPROXIMATELY THE SAME TIME EVERY DAY UNTIL THE PACK IS EMPTY. 2. Try to associate taking your pill with some regular activity such as eating a meal or going to bed. 3. Do not skip pills even if you have bleeding between monthly periods or feel sick to your stomach (nausea). 4. Do not skip pills even if you do not have sex very often. 5. WHEN YOU FINISH A PACK
- 21 PILLS
- 28 PILLS
WAIT SEVEN DAYS to start the next pack. You will have your period during that week.
Start the next pack ON THE NEXT DAY. Take one pill every day. Do not wait any days between packs.
Usual Dose
Overdose
Overdosage may cause nausea, vomiting, breast tenderness, dizziness, abdominal pain, and fatigue/drowsiness. Withdrawal bleeding may occur in females. In case of overdosage, contact your doctor or pharmacist or call your local poison control centre immediately.
Missed Dose
WHAT TO DO IF YOU MISS PILLS
Birth control pills may not be as effective if you miss pills. The following chart outlines the actions you should take if you miss one or more of your birth control pills. Match the number of pills missed with the appropriate starting time for your type of pill pack.

NOTE: 28-DAY PACK-
If you forget any of the seven
“reminder” pills (without hormones) in Week 4, just safely
dispose of the pills you missed. Then keep taking one pill
each day until the pack is empty. You do not need to use a
back-up method.
Always be sure you have on hand
- a non-hormonal back-up method of birth control (such as latex condoms and spermicidal foam or gel) in case you miss pills, and
- an extra, full pack of pills.
IF YOU FORGET MORE THAN ONE PILL TWO MONTHS IN A ROW, TALK TO YOUR DOCTOR OR CLINIC about ways to make pill-taking easier or about using another method of birth control.
Non-Contraceptive Benefits of Birth Control Pills:
Several health advantages have been linked to the use of birth
control pills.
- Combination estrogen and progestin birth control pills reduce the incidence of cancer of the uterus and ovaries.
- Birth control pills reduce the likelihood of developing benign (non-cancerous) breast disease and ovarian cysts.
- Users of birth control pills lose less menstrual blood and have more regular cycles. The risk of developing irondeficiency anemia is thus reduced.
- There may be a decrease in painful menstruation and premenstrual syndrome (PMS).
- Acne, excessive hair growth and male hormone-related disorders also may be improved.
Side effects and what to do about them
Some users of birth control pills have unpleasant side effects.
Most side effects are temporary and are not hazardous to the
health.
There may be tenderness of the breast, nausea, and vomiting.
Some users will experience weight gain or loss. Many of
these side effects occurred with high-dose combination birth
control pills. These side effects are less common with the
low-dose pills prescribed today.
Unexpected vaginal bleeding or spotting and changes in the
usual menstrual period may also occur. These side effects
usually disappear after the first few cycles. They are not an
indication to stop taking birth control pills. Unless more
significant complications occur, a decision to stop using the
pill or to change the brand of pill should be made only after
three consecutive months of use. Occasionally, users develop
high blood pressure that may require stopping the use of birth
control pills.
Other side effects may include:
- growth of pre-existing fibroid tumours of the uterus
- an increase or decrease in hair growth, sex drive and appetite;
- skin pigmentation;
- headaches;
- abnormal liver test, nausea, vomiting, severe pain or lump in the abdomen;
- rash; and/or
- vaginal infections.
Infrequently, there is a need to change contact lens
prescription or an inability to use contact lenses.
A woman's menstrual period may be delayed after stopping birth
control pills. There is no evidence that the use of the pill leads to
a decrease in fertility. As mentioned, it is wise to delay starting a
pregnancy for one menstrual period after stopping birth control
pills.
Symptom / effect | Talk with your doctor or pharmacist only if severe | Talk with your doctor or pharmacist in all cases | Stop taking drug and call with your doctor or pharmacist |
---|---|---|---|
Uncommon | |||
Sharp pain in the chest, coughing blood, or sudden shortness of breath | ✔ | ||
Pain or swelling in the leg | ✔ | ||
Crushing chest pain or heaviness | ✔ | ||
Sudden severe or worsening headache or vomiting, dizziness or fainting, disturbance of vision or speech, or weakness or numbness in an arm or leg | ✔ | ||
Sudden partial or complete loss of vision | ✔ | ||
Abdominal liver test and/or, nausea, vomiting severe pain or lump in the abdomen | ✔ | ||
Persistent sad mood | ✔ | ||
Yellowing of the skin or eyes (jaundice) | ✔ | ||
Unusual swelling of the extremities | ✔ | ||
Breast lumps | ✔ | ||
Unexpected (Abnormal) vaginal bleeding | ✔ |
This is not a complete list of side effects. For any unexpected effects while taking AVIANE, contact your doctor or pharmacist.
How to store
Store at room temperature (15-30ºC).
AVIANE 21 and AVIANE 28 should be protected from light
once opened using the protective covering provided. Keep out
of reach of children and pets.
Reporting side effects
You can report any suspected side effects associated with the use of health products to Health Canada by:
- Visiting the Web page on Adverse Reaction Reporting www.canada.ca/en/health-canada/services/drugshealth-products/medeffectcanada/adverse-reactionreporting.html for information on how to report online, by mail or by fax; or
- Calling toll-free at 1-866-234-2345.
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.
More information
This leaflet is part III of a three-part “Product Monograph" published when AVIANE 21 and AVIANE 28 was approved for sale in Canada and is designed specifically for Consumers. This leaflet is a summary and will not tell you everything about AVIANE 21 and AVIANE 28. Contact your doctor or pharmacist if you have any questions about the drug.
This document plus the full product monograph, prepared for health professionals can be found by contacting Teva Canada Limited by:
Phone: 1-800-268-4127 ext. 3;
Email: druginfo@tevacanada.com; or
Fax: 1-416-335-4472
This leaflet was prepared by Teva Canada Limited, Toronto,
Canada, M1B 2K9.
Last revised: March 15, 2019